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This page was prepared by Lynn Kash, RN, Internet Nursing Guide
Pennsylvania Nurses,Emergency Department
http://www.nursefriendly.com/kash/

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Colzal(Balsalazide disodium), Clinical Results, Center Watch:"Two randomized, double-blind studies have been conducted using Colazol to determine its effectiveness in treating mild to moderate ulcerative colitis. The first study consisted of 103 subjects with active ulcerative colitis who showed evidence of spontaneously bleeding mucosa of the colon. These subjects were randomized and treated with either 6.75 grams/day of balsalazide or 2.25 grams/day. The efficacy endpoint of the trial was reduction in rectal bleeding, pain, stool frequency and other assessed symptoms. The study showed a statistically significant difference in efficacy between the high and low dose test groups."
http://www.centerwatch.com/patient/drugs/dru628.html

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Colazal(Balsalazide disodium), FDA Approves Colazal (Balsalazide Disodium) For Ulcerative Colitis, July 24, 2000, Doctor's Guide:"Salix Pharmaceuticals, Ltd announced that Colazal™ (balsalazide disodium) has been approved by the U.S. Food and Drug Administration (FDA) for marketing in the United States for the treatment of mildly to moderately active ulcerative colitis, a chronic and debilitating inflammatory disease of the gastrointestinal tract."
http://www.pslgroup.com/dg/1da6ea.htm

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Balsalazide, What are the common side effects, Health and Age:"Headache. Belly pain and cramps. Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help. Diarrhea. Muscle aches and pains. Lung infections."
http://www.healthandage.com/html/res/com/ConsDrugs/Balsalazidecd.html

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Colazol, Why is this drug prescribed, Health Square:"Colazal is used in the treatment of mild to moderate ulcerative colitis (chronic inflammation and ulceration of the lower intestine). It is an anti-inflammatory medicine specially formulated to release the active ingredient, mesalamine, directly to the lining of the colon. Its ability to provide relief without the severe side effects found with similar drugs is believed to be due to this localized drug delivery mechanism."
http://www.healthsquare.com/newrx/col1560.htm

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Balsalazide(Colazol), What is Blasalazide, Jackson Gastroenterology:"Balsalazide is an anti-inflammatory drug which acts on the lining of the colon to reduce inflammation. Bacteria in the colon activate this drug by releasing the active anti-inflammatory drug, mesalamine. http://www.gicare.com/pated/balsalazide.htm

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Balsalazide, Description, MEDLINEplus:"Balsalazide (bal–SAL–a–zide ) helps to decrease inflammation in the colon by blocking the production of certain chemicals that cause the bowel to become overactive. This medicine is available only with your doctor's prescription, in the following dosage form: Oral ."
Office of Communications and Public Liaison National Library of Medicine
8600 Rockville Pike Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450 email: publicinfo@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500233.html

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Colazal, Why is this drug prescribed, PDR.net:"Colazal is used in the treatment of mild to moderate ulcerative colitis (chronic inflammation and ulceration of the lower intestine). It is an anti-inflammatory medicine specially formulated to release the active ingredient, mesalamine, directly to the lining of the colon. Its ability to provide relief without the severe side effects found with similar drugs is believed to be due to this localized drug delivery mechanism."
http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/col1560.shtml

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Balsalazide, Dosage and Administration, RXlist:"For Treatment of Active Ulcerative Colitis the usual dose in adults is three 750 mg COLAZAL ™ capsules to be taken three times a day for a total daily dose of 6.75 grams for a duration of 8 weeks. Some patients in the clinical trials required treatment for up to 12 weeks."
http://www.rxlist.com/cgi/generic2/balsalazide_ids.htm

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Balsalazide Sodium, Description, xReferences:"An aminosalicylate that is used for the treatment of mild to moderate ulcerative colitis; it is converted to mesalazine in the body. Balsalazide is available as capsules on prescription only."
http://www.xrefer.com/entry/472432

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