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ACE-inhibitors for renal disease and diabetes? Bandolier:"Bandolier has heard it said that most patients with chronic renal disease or diabetes should be taking ACE inhibitors. Evidence seems to be accumulating, in the shape of systematic reviews and large randomised trials. A brief review, then, of some of the evidence on outcomes, seems in order." ******************************************************
ACE Inhibitors in the treatment of chronic heart failure, Bandolier: Effective and cost-effective
Chronic heart failure (CHF) is the syndrome of breathlessness, fatigue and fluid retention resulting in an impaired ability of the heart to pump properly. The commonest causes are coronary heart disease (CHD) and primary heart muscle diseases (cardiomyopathies), with heart valve disease less common. Heart failure is over-diagnosed (especially in the elderly) and is best confirmed using cardiac ultrasound [1]. Only a minority of people in the community with suspected CHF receive this investigation [2]." ******************************************************
How to Take Your Medicine Angiotensin-Converting Enzyme Inhibitors Food and Drug Administration (FDA): ******************************************************
ACE Inhibitors and Angiotensin II Receptor Antagonists, Huffington Center on Aging:"ACE inhibitors are essential for treatment of CHF due to systolic dysfunction (Garg, AHCPR guidelines). Older people may show an exaggerated drop in blood pressure after the first dose of an ACE inhibitor. Therefore, we give a short-acting ACE inhibitor such as Captropril and have the patient's blood pressure observed for several hours. Longer-acting ACE inhibitors are given when the patient's tolerance to Captropril is established. This is another medication which can lead to hypotension. Use ACE inhibitors with care if the patient is on other drugs with hypotensive potential (e.g., antidepressants)." ******************************************************
Angiotensin-Converting Enzyme Inhibition In Myocardial Infarction, Pulsus.com: ******************************************************
ACE-Inhibitors Score High In Reducing Heart Attack Deaths PSL Group: ******************************************************
Ace Inhibitors:"Ace inhibitors inhibit (slow down) "angiotensin converting enzymes" or ACEs, which are part of our "renin-angiotensin system." This system helps control blood pressure, kidney function and blood volume. ACEs breakdown the chemicals in the body that expand your blood vessels and they constrict (shrink) your blood vessels very powerfully." ******************************************************
Jon's ACE Inhibitor Page:"Please try to read this stuff. I know it's complicated and boring but I've tried to make it easier to understand, and all CHFers really need to know this. If you can follow the explanations below, you'll have a basic understanding of why ACE inhibitors are the most important drug in CHF treatment. Click on words that are links and you'll get more information. And by all means, please e-mail me with suggestions." ******************************************************
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Created on Saturday, May 22, 1999 Last updated by Andrew Lopez, RN on Thursday, May 31, 2007 |
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